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Symbol
Name
ID
Dot1l
DOT1 like histone lysine methyltransferase
MGI:2143886
Phenotype annotations related to cardiovascular system
Darker colors indicate more annotations

Mouse Phenotypes
abnormal vitelline vasculature morphology
abnormal heart morphology
increased heart weight
enlarged heart
increased heart left ventricle size
dilated heart ventricle
cardiac interstitial fibrosis
dilated cardiomyopathy
decreased cardiac output
increased fetal cardiomyocyte proliferation
prolonged RR interval
prolonged PR interval
atrioventricular block
prolonged P wave
prolonged QRS complex duration
heart block
increased cardiomyocyte apoptosis
Availability Mouse Genotype
Dot1ltm1.1Tche/Dot1ltm1.1Tche
Dot1ltm1Tche/Dot1ltm1.1Tche
Tg(Myhca-cre)1Abel/0  (conditional)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory